Healthcare Archives | 91³Ô¹ÏÍø News Central Florida Research, Arts, Technology, Student Life and College News, Stories and More Tue, 03 Nov 2026 16:13:03 +0000 en-US hourly 1 https://wordpress.org/?v=7.1.4 /wp-content/blogs.dir/20/files/2019/05/cropped-logo-150x150.png Healthcare Archives | 91³Ô¹ÏÍø News 32 32 Zaby and Suree Vyas Investment Helps Shape the Next Generation of Healthcare Leaders /news/zaby-and-suree-vyas-investment-helps-shape-the-next-generation-of-healthcare-leaders/ Tue, 03 Nov 2026 13:30:30 +0000 /news/?p=156555 This gift — which is recognized with a newly named tower and classroom honoring a legacy of service, opportunity and philanthropy — supports scholarships for future physicians.

]]>
A transformational gift from Zaby and Suree Vyas is helping future physicians launch careers of service while creating a lasting legacy at 91³Ô¹ÏÍø’s College of Medicine, where the university officially unveiled the Suree & Zaby Vyas, MD Tower and Suree & Zaby Vyas, MD Classroom on Nov. 2.

The gift supports the Dean’s Excellence Fund and the S&Z Vyas Charitable Foundation Endowed MD Scholarship, expanding opportunities for future physicians and advancing 91³Ô¹ÏÍø’s Go For Launch campaign priorities.

“Dr. Zaby and Suree Vyas understand that excellence in healthcare begins with investing in people,” says Deborah German, dean of the 91³Ô¹ÏÍø College of Medicine. “Their generosity will help talented students pursue their dreams of becoming physicians while providing the resources that allow our college to continue raising the standard of medical education. Their gift embodies the goals of by supporting student success and helping 91³Ô¹ÏÍø maximize excellence for generations to come.”

For 91³Ô¹ÏÍø College of Medicine student Nicole Stevens ’25, donor support helped turn possibility into reality. A mother of three and nontraditional student, Stevens shared how scholarships, mentorship and research opportunities empowered her to pursue medicine and redefine what she believed was possible for herself and her family.

The clock tower stands at the center of 91³Ô¹ÏÍø’s Health Sciences Campus and serves as an iconic symbol of the College of Medicine, welcoming students, faculty and visitors while reflecting the importance of time, innovation and excellence in training the next generation of physicians. All those entering the medical education building, where every 91³Ô¹ÏÍø future physician is trained, will see the commitment that the Vyas’ have made to the college, to the healthcare landscape of Florida and to the future generation of healthcare providers.

“One represents the daily work of learning, discovery and growthâ€� says President Alexander N. Cartwright. “The other serves as a bold and enduring presence on the horizon. Together, they reflect the lasting impact the Vyas family is making on 91³Ô¹ÏÍø and the future of healthcare.”

After being forced to leave Uganda in 1972, the newly married couple rebuilt their lives in England before eventually settling in Central Florida, where Vyas established a successful family medicine practice. Their journey shaped a lifelong commitment to expanding opportunity for others, particularly future healthcare professionals.The Suree & Zaby Vyas Foundation was created to invest in the next generation of caregivers by supporting students in 91³Ô¹ÏÍø’s College of Medicine and College of Nursing and creating an endowment to provide perpetual scholarship support. Their name is also recognized inside the Dr. Phillips Nursing Pavilion, home of the College of Nursing with the Zaby & Suree Vyas Collaboration Concourse.

]]>
91³Ô¹ÏÍø Researcher Investigates Mechanisms of Nicotine Addiction /news/ucf-researcher-investigates-mechanisms-of-nicotine-addiction/ Fri, 25 Sep 2026 13:00:14 +0000 /news/?p=155467 Through a National Institutes of Health grant, College of Medicine Assistant Professor Cali Calarco is investigating how brain cells respond to nicotine and influence behavior.

]]>
91³Ô¹ÏÍø assistant professor and researcher , with the College of Medicine‘s Burnett School of Biomedical Sciences, is exploring how nicotine affects brain cells, providing insights that could ultimately help improve treatments for addiction.

Through a nearly five-year, $943,000-plus grant from the National Institutes of Health, Calarco’s lab is examining how neurons — nerve cells in the brain — and their molecules change when exposed to nicotine and other drugs. The goal is to understand how microscopic changes in the brain eventually influence behavioral decisions, including those associated with addiction.

“We want to understand what’s really influencing the neuron,â€� says Calarco, who began work on this project in 2024 as a postdoctoral scholar at the University of Maryland, Baltimore, before joining 91³Ô¹ÏÍø in January as an assistant professor. “Which component is critical for the neuron function that leads to drug-seeking behavior?â€�

For this research, Calarco’s lab is focused on the nucleus accumbens, an area of the brain involved in reward, learning and behavior.

“I call it a little computer that integrates a lot of signals that come in relationship to reward learning from a lot of other parts of the brain to guide behavioral choices,� she says.

“We want to understand what’s really influencing the neuron. Which component is critical for the neuron function that leads to drug-seeking behavior?â€� — Cali Calarco, assistant professor

The nucleus accumbens contains multiple types of brain cells, and Calarco’s research examines how individual cell types respond to nicotine and other drugs. Her lab is particularly interested in mitochondria, the structures within cells that produce the energy they need to function. Recent studies suggest mitochondria may also play an important role in drug-seeking behavior.

“Mitochondria have been underappreciated in neurons previously,� she says. “Neurons are incredibly complex cells that do incredibly complex tasks, both electrically and chemically that require a ton of energy, so we knew they were really important. But mitochondria also influence how neurons communicate with each other. They’re super important for gene transcription and translation and for steroid hormone production.�

91³Ô¹ÏÍø Assistant Professor Cali Calarco stands with six researchers wearing lab coats in a biomedical sciences laboratory.
Assistant Professor Cali Calarco (left) with researchers in the Burnett School of Biomedical Sciences. Calarco’s research examines how brain cells respond to nicotine and how cellular changes may influence behaviors associated with addiction. (Photo courtesy of Cali Calarco)

By understanding addiction at the molecular level, researchers may ultimately be able to develop better treatments for substance use disorder.

“There aren’t that many substance use disorder treatments, and the ones available only work for a subset of people,� she says. “There is room for improvement in nicotine use disorder therapies, and new pathway targets may provide more effective treatments with fewer side effects.�

Nicotine use has persisted even as the products used to consume it have changed. Calarco compares the trend to a game of whack-a-mole, with new nicotine products gaining popularity as older ones decline. While cigarette smoking has declined, consumers now have access to products such as e-cigarettes and nicotine pouches placed between the lips and gum. According to data from the FDA and CDC’s 2025 National Youth Tobacco Survey, nicotine pouch use nearly quadrupled among U.S. youth and young adults between 2022 and 2025.

While her research is focused on nicotine, Calarco says her findings could have implications for other substances and even social media addiction.

Calarco earned her doctorate in neuroscience from Yale University before conducting postdoctoral research at the University of Maryland, Baltimore, where she studied mitochondria and cocaine-seeking behavior. She joined the 91³Ô¹ÏÍø College of Medicine’s Burnett School of Biomedical Sciences in January 2026.


Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under award number K01DA061048. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. 

]]>
Calarco Lab Team 91³Ô¹ÏÍø Assistant Professor Cali Calarco, left, with researchers in the Burnett School of Biomedical Sciences. Calarco’s research examines how brain cells respond to nicotine and how cellular changes may influence behaviors associated with addiction. (Photo provided by Cali Calarco)
91³Ô¹ÏÍø Researcher Identifies 10 Potential Treatments for Rare Nerve Tumor in Children /news/ucf-researcher-identifies-10-potential-treatments-for-rare-nerve-tumor-in-children/ Wed, 23 Sep 2026 14:00:59 +0000 /news/?p=155281 Using artificial intelligence-generated data, Pegasus Professor Cristina Fernández-Valle and her team are screening existing FDA-approved drugs for their potential to treat schwannoma tumors.

]]>

What if an existing drug could be repurposed to treat a rare disease?

That’s the question 91³Ô¹ÏÍø researchers are exploring with the help of artificial intelligence (AI) to find a cure for rare nerve tumors that can cause paralysis, hearing and balance loss.

Led by 91³Ô¹ÏÍø College of Medicine Pegasus Professor Cristina Fernández-Valle, the team is investigating whether medications already approved by the U.S. Food and Drug Administration for other conditions could be swiftly repurposed to treat schwannoma tumors.

The researchers have narrowed a field of about 200 potential drugs to 10 of interest, with three emerging as the most favorable targets.

Their goal is to find new treatment options for patients with Neurofibromatosis type 2 (NF2)-related schwannomatosis. The genetic disorder causes benign tumors to develop on nerves throughout the body and head. As the tumors grow, they can damage nerves responsible for movement and sensation, including those needed to hear and balance.

The disease affects about one in 25,000 newborns worldwide, according to the Children’s Tumor Foundation, with symptoms often appearing during adolescence and early adulthood. When diagnosed in children, the disorder can be severe and may require multiple surgeries during puberty to reduce tumor size and prevent further loss of function. The Children’s Tumor Foundation is supporting 91³Ô¹Ï꿉۪s research with a $280,020 grant.

“The Children’s Tumor Foundation was critical to us because they fund the exploratory research that helps advance science,� Fernández-Valle says. “All of this foundational data is needed to attract the additional support needed to demonstrate a treatment holds real promise.�

A 91³Ô¹ÏÍø student uses a pipette while 91³Ô¹ÏÍø Professor Cristina Fernández-Valle observes him in a research lab.
Pegasus Professor Cristina Fernández-Valle observes 91³Ô¹ÏÍø College of Medicine M.D./Ph.D. candidate Ethan Hass as he prepares medication samples for efficacy testing.

Looking for Treatments Beyond Surgery

Schwann cells normally help repair nerves and transmit electrical signals throughout the nervous system. In patients with NF2, however, these cells can form visible tumors that cause chronic pain and neurological issues depending on the affected spinal or cranial nerve.

Current treatments center on surgery and radiation, but removing these tumors can be challenging without damaging critical nerves, including those that affect hearing. Surgery also is not curative, as tumors can regrow.

That’s why the research team is looking beyond surgery to potential drug therapies.

While schwannomas are not cancerous, the researchers believe some cancer-fighting drugs may help patients with NF2.

The research began with an AI model called TxGNN, developed by Marinka Zitnik’s laboratory at Harvard Medical School. The model analyzes data and biological mechanisms across thousands of diseases and FDA-approved drugs to identify potential treatments for a queried disease.

“It essentially generates a map for a disease or condition, like schwannomas, and finds overlaps in targeting similar pathways or related diseases,â€� says Ethan Hass, a 91³Ô¹ÏÍø College of Medicine M.D./Ph.D. candidate working in the lab.

Researchers at Sage Bionetworks used the TxGNN model to identify about 200 FDA-approved medications that could potentially benefit schwannoma patients. Fernández-Valle’s team then used an innovative imaging system to observe how each drug affected human schwannoma cells.

Using a camera inside a microscope, the team watched how schwannoma cells in a dish reacted to small amounts of each drug. The most promising candidates – medications currently used to treat diseases as varied as lung cancer and acne – stopped tumor cell growth by impacting different cellular mechanisms.

A Step Towards Personalized Treatment

The research continues.

The 91³Ô¹ÏÍø scientists are determining therapeutic doses for the most promising drugs using patient-derived schwannoma cells. They’re also studying how the drugs affect the tumor growth pathways at the RNA level.

Ultimately, the researchers hope their findings will help identify drug combinations tailored to individual patients. Complicated and understudied genetic conditions like NF2-related schwannomatosis often require treatments that address multiple targets, Fernández-Valle says.

“I think this work is encouraging, and I’d say like with many cancers, you need a cocktail of drugs to treat it,� she says. “I think what we’re doing here is helping to identify some of the ingredients you might need to make an effective cocktail.�

91³Ô¹ÏÍø Professor Cristina Fernández-Valle poses with four student researchers in a lab.
From left: Pegasus Professor Cristina Fernández-Valle, biomedical sciences undergraduate students Alfonso Aviles and Amanda Nunez-Ferreira, materials science and engineering doctoral candidate Alex Sutton and M.D./Ph.D. student Ethan Hass.

From Lab Bench to Patient Bedside

The project also provides 91³Ô¹ÏÍø students with the opportunity to participate in research that can make a real-world impact.

Since joining Fernández-Valle’s lab, Hass says his interest in caring for patients with difficult neurologic conditions has grown.

“As an M.D./Ph.D. student, translation is the magic word for me,� he says. “I absolutely love seeing research that can be brought from the bench to the bedside. I want to be that bridge between patients and research.�

]]>
Cristina-Valle and Ethan-Hass_ Schwannoma research Cristina Valle and students_ Schwannoma research
Med Student Driven to Create Hope Through Cancer Research Earns Inaugural Award /news/med-student-driven-to-create-hope-through-cancer-research-earns-inaugural-award/ Thu, 27 Aug 2026 15:14:42 +0000 /news/?p=154959 The winner of the inaugural Dean Deborah C. German, M.D. FIRE Impact Award came to 91³Ô¹ÏÍø because of the College of Medicine’s focus on research.

]]>
91³Ô¹ÏÍø medical student Natalya Kramer lost her grandfather to lymphoma, inspiring her to pursue medicine with hopes of caring for cancer patients and their families.

That dedication and her passion for research recently earned Kramer the inaugural Dean Deborah C. German, M.D. FIRE (Focused Individualized Research Experience) Impact Award, an honor named after the founding dean of 91³Ô¹Ï꿉۪s College of Medicine who created the FIRE course, which requires every student to conduct a two-year research project.

German announced earlier this year that she is transitioning from her role and will remain at 91³Ô¹ÏÍø for a year as an advisor to the president and provost on health affairs. FIRE leaders created the award to honor German’s legacy of scientific discovery as part of medical training, an educational component that makes 91³Ô¹Ï꿉۪s medical school unique nationally.

“I want our students to develop a spirit of inquiry. I want every 91³Ô¹ÏÍø physician not to be afraid to seek answers to medicine’s unanswered questions.â€� — Deborah German, College of Medicine dean

“I want our students to develop a spirit of inquiry,â€� German told Kramer as she presented her with the award. “I want every 91³Ô¹ÏÍø physician not to be afraid to seek answers to medicine’s unanswered questions.â€�

After earning an undergraduate degree the University of South Florida, Kramer decided to attend 91³Ô¹ÏÍø in part because the FIRE course was one reason she came to 91³Ô¹ÏÍø.

“I wanted to combine research with clinical care,� she says.

Her FIRE project focused on glioblastoma, an aggressive brain cancer with a five-year survival rate of only 5% to 7%, according to the Mayo Clinic. Even if surgery, chemotherapy and radiation initially stop the cancer, it usually returns and becomes stronger. Kramer says she wanted to know why.

With support from her FIRE mentor, Kiminobu Sugaya, head of the College of Medicine’s neuroscience research division, she discovered that extracellular vesicles responsible for cell-to-cell communication may influence non-cancer cells to take on cancer-like properties.

Medical student Natalya Kramer (center, left) with 91³Ô¹ÏÍø College of Medicine founding Dean Deborah German (center, right) and co-directors of the FIRE course Lane Coffee (left) and Robert Hines (right).

The new award goes to the student whose research shows the greatest potential impact to medicine and/or biomedical research. College of Medicine faculty and fellow students chose Kramer for the award during the FIRE Conference.

“It is our privilege to establish this award in honor of Dean German,� say Robert Hines and Lane Coffee, co-directors of the FIRE course. “When establishing this medical school, she realized the importance of rigorous scientific inquiry, and our students have benefited from — and will continue to benefit from — this course within the curriculum.�

]]>
2026-Dean’s-Research-FIRE-award,-Dr.-German-&-Natalya–(5) Natalya Kramer (left) with 91³Ô¹ÏÍø College of Medicine founding Dean Deborah German (right).
FAA Executive Physician/Scientist Joins 91³Ô¹ÏÍø Aerospace Medicine Team /news/faa-executive-physician-scientist-joins-ucf-aerospace-medicine-team/ Fri, 21 Aug 2026 13:00:08 +0000 /news/?p=154760 After 34 years with the FAA, Melchor Antuñano joins 91³Ô¹ÏÍø to create a new aerospace medicine master’s degree and residency program, as well enhance safety for astronauts, pilots and flight passengers.

]]>

He’s an experienced skydiver, private pilot and scuba diver whose hero since childhood has been moon-walker Neil Armstrong. And now Melchor Antuñano is a 91³Ô¹ÏÍø Knight.

After 34 years with the Federal Aviation Administration (FAA) — the longest term for any senior executive in the agency’s history — Antuñano has joined the College of Medicine’s team as a professor, and chief technologist and medical innovation officer. In these roles he’ll help design new procedures and technologies to keep astronauts, pilots and airplane passengers safer and help create a new 91³Ô¹ÏÍø master’s degree in aerospace medicine and a residency program for aerospace medicine physicians. He’ll also teach across 91³Ô¹ÏÍø colleges.

“Being part of this outstanding visionary team gives me the opportunity not only to help advance the field I love, but also to inspire, educate and mentor the next generation of physicians, scientists and innovators.â€� — Melchor Antuñano, 91³Ô¹ÏÍø aerospace medicine medical innovation officer

Antuñano says a career in aerospace medicine has given him the “opportunity to continually learn, adapt and contribute to a specialty defined by innovation, exploration, and discovery.�

“Joining the 91³Ô¹ÏÍø College of Medicine represents a new and exciting chapter in that journey,â€� he continues. “Being part of this outstanding visionary team gives me the opportunity not only to help advance the field I love, but also to inspire, educate and mentor the next generation of physicians, scientists and innovators.â€�

He is the newest leader to join 91³Ô¹Ï꿉۪s new Center for Aerospace and Extreme Environments Medicine , a multidisciplinary center includes faculty experts in medicine, engineering, computer science, psychology, arts and educational leadership who will work together to research and develop new technologies for keeping space travelers healthy as well as soldiers on military missions, deep sea explorers, and mountain climbers.

“Dr. Antuñano brings to 91³Ô¹ÏÍø an extraordinary combination of operational experience, scientific leadership, innovation and a lifelong commitment to aerospace medicine,â€� says Emmanuel Urquieta, vice chair for aerospace medicine and director of CASEEM. “For more than three decades, he helped shape aerospace medicine and safety at the national and international levels. Having someone of his caliber join our team is transformative as we build a comprehensive aerospace medicine program that integrates clinical care, education, research and technology development.â€�

A Resourceful First Responder Before Medical School

Born in Mexico City, Antuñano had two dreams as a child: to be a doctor and fly airplanes. Before entering medical school at the National Autonomous University of Mexico School of Medicine, he volunteered with the Red Cross and the country’s rescue squad as a paramedic, rescue worker and EMT. He couldn’t afford to buy a red emergency light for his car. So he made one using a pot.

“My parents always instilled in my sisters and me the importance of doing our best, persevering in the face of adversity, planning ahead and learning from our mistakes,� he says. “I learned from my parents the importance of being kind, fair and respectful to everybody.�

He learned about aviation medicine during medical school and volunteered at the Mexican Government’s National Center of Aviation Medicine, where he learned about aviation physiology (including altitude chamber operations), human factors in aircraft accident investigation and pilot medical certification.

Melchor Antuñano flying in a biplane
Melchor Antuñano flying in a biplane. (Photo courtesy of Melchor Antuñano)

Impact Fueled by Taking Initiative

Next came residency. Antuñano says he came to America because the only civilian aerospace medicine residency program was at Wright State University School of Medicine in Dayton, Ohio.

He learned about this program by writing letters to senior U.S. federal government officials — including then President Ronald Reagan — inquiring where to pursue postgraduate training in aviation medicine in the U.S. He was accepted into the residency.

“That opportunity allowed me to pursue my professional dream and meet aerospace medicine physicians from all over the world,� he says.

Antuñano also earned a master’s in aerospace medicine at Wright State. His research was using a portable head cooling system to protect U.S. Air Force personnel from heat exposure. He built his lab in the kitchen of the residents’ lounge. He turned up the heat, then added oil and air heaters to create a thermal chamber. His experimental subjects were his classmates. He earned the Aerospace Medical Association’s Young Investigator Award for his initiative.

Melchor Antuñano
Melchor Antuñano (left) with astronaut Buzz Aldrin. (Photo courtesy of Melchor Antuñano)

After residency, he received a two-year postdoctoral research fellowship from the National Research Council of the U.S. National Academy of Sciences, Engineering and Medicine at the U.S. Air Force School of Aerospace Medicine. After that, he was hired as a contract scientist for the school to work on personal cooling technology for individuals wearing nuclear, biological and chemical protective suits.

Antuñano joined the FAA in 1992 and served as manager of the Medical Education Division and the Medical Certification Division at the agency’s Civil Aerospace Medical Institute (CAMI) in Oklahoma City. The institute is responsible for medically certifying that the nation’s pilots are physically fit to fly, training the physicians who perform the physical exams in the U.S. and in 90 countries worldwide, and conducting safety-related aerospace medicine and human factors research. He became CAMI’s director in 2001 and retired earlier this year as the longest serving director in history.

Steering the Future of Aerospace Medicine at 91³Ô¹ÏÍø

“A leader has the responsibility to make more leaders,â€� he says. “Look for stars in the making — encourage them, support them and help turn them into future leaders.â€� — Melchor Antuñano, 91³Ô¹ÏÍø aerospace medicine medical innovation officer

As the commercial space industry expands and humans prepare for longer missions to the moon, Mars and beyond, 91³Ô¹Ï꿉۪s College of Medicine is charting a new frontier in healthcare. The goal: explore how factors such as microgravity, radiation and isolation impact the human body in space and how that knowledge can drive innovation into diagnostics, treatment and disease prevention for patients on Earth.

As part of that effort, the aerospace medicine team is developing courses for students across the university and building a lab that will design, create and test the next generation of medical equipment to keep space travelers healthy. The team just opened the 91³Ô¹ÏÍø Aerospace Medicine Clinic to provide medical certification exams for astronauts and pilots across the region.

Antuñano says he is excited about the future and his role in advancing aerospace medicine research while training the next generation of aerospace physicians.

“A leader has the responsibility to make more leaders,� he says. “Look for stars in the making — encourage them, support them and help turn them into future leaders.�

 

]]>
Melchor Antuñano_Flying Melchor Antuñano flying in a biplane. (Photo courtesy of Melchor Antuñano) Melchor Antuñano and Buzz Aldrin
91³Ô¹ÏÍø Scientist to Explore Precise Treatment Targeting Weak Spots in Lyme Disease Bacteria /news/ucf-scientist-to-explore-precise-treatment-targeting-weak-spots-in-lyme-disease-bacteria/ Thu, 13 Aug 2026 13:30:56 +0000 /news/?p=154614 Through her third consecutive NIH grant renewal, Mollie Jewett aims to “starveâ€� Borrelia burgdorferi, preventing the tick-borne bacteria from spreading in humans and causing Lyme disease.

]]>
Triggered by a near-painless tick bite, Lyme disease causes severe pain and inflammation for more than 475,000 people in the U.S annually, according to the Centers for Disease Control.

Medicine can treat infections after people get sick, but 91³Ô¹ÏÍø infectious disease expert Mollie Jewett is seeking to halt Borrelia burgdorferi bacteria, which causes Lyme disease, in its tracks without relying on general antibiotics. Her goal: “starveâ€� the bacteria of the nutrients they need to function before they spread through the human body.

Jewett, professor and head of the Immunity and Pathogenesis Research Division at 91³Ô¹Ï꿉۪s College of Medicine, is supported by a recently renewed five-year, $2.5 million grant from the National Institutes of Health.

91³Ô¹ÏÍø infectious disease expert Mollie Jewett smiles while wearing a white lab coat in a research lab.
91³Ô¹ÏÍø infectious disease expert Mollie Jewett.

She is entering a third consecutive federally funded research cycle with $513,314 received this year. Jewett’s research builds upon more than a decade of discoveries that have narrowed the search for ways to stop B. burgdorferi from triggering Lyme disease, one of the nation’s most common vector-borne diseases. Her team includes a 91³Ô¹ÏÍø undergraduate who occasionally struggled to walk because of pain from Lyme disease.

The disease is spread by blacklegged ticks that become infected after biting mammals or birds carrying the bacteria. The ticks are so small, humans often don’t notice they have been bitten. Symptoms include fever, chills, headache and fatigue, which often are misdiagnosed as a virus or the flu. Even after treatment, Lyme disease patients can face complications including nervous system and heart issues, severe fatigue and arthritic pain.

The disease is most commonly found in Maine to Virginia and in the upper Midwest but is spreading as suburban growth enters wildlife areas. Florida reports few cases of Lyme disease annually, but travelers who go to endemic areas like New England are at increased risk.

A New Approach to Battle Borrelia

91³Ô¹ÏÍø researchers are focused on how B. burgdorferi manages to survive and thrive as it spreads in ticks and mammals to humans.

“The bacteria need to adapt to two different environments, and so we want to know how it does that,� Jewett says. “We’re looking at what the bacteria eat and what it needs to survive. In our lab, we call Borrelia a wimpy pathogen because it can’t make a lot of the nutrients it needs on its own, and so it scavenges what it needs from wherever it is.�

Researchers examine a petri dish on an illuminated light box in a lab.
Mollie Jewett and her lab analyze the purification of a novel riboflavin-dependent protein important for Borrelia burgdorferi metabolism.

The first iteration of the NIH grant allowed the scientists to screen all of the bacteria’s genes that might be important for the infection. With the second grant, Jewett targeted three genes that appeared to play a role in spreading the infection from a bite on the skin to other parts of the human body.

“One of these three genes we found is important to the ability of the bacteria to consume riboflavin. We want to target this gene and see if we can starve the bacteria.” — Mollie Jewett, 91³Ô¹ÏÍø infectious disease expert

Now they have focused on riboflavin, commonly known as vitamin B2, after discovering that B. burgdorferi salvages the vitamin from each host to sustain itself.

“One of these three genes we found is important to the ability of the bacteria to consume riboflavin,� Jewett says. “We know that riboflavin is a precursor for other cellular activities that are important to the metabolism of the bacteria. Essentially, we want to target this gene and see if we can starve the bacteria.�

If their theory is successful, it could lead to therapies specific to B. burgdorferi that would prevent successful bacterial infection by limiting its riboflavin uptake. An advantage of such potential treatments would be that patients don’t have to take general antibiotics that can also harm the body’s good bacteria and increase risks for antibiotic-resistant bacteria.

The 91³Ô¹ÏÍø team is collaborating with Baylor University scientists to trace exactly how riboflavin is used by the bacteria.

Researchers examine a petri dish on an illuminated light box in a lab.
Biomedical sciences doctoral student Anna Schulz ’25MS (left) uses genetic approaches to characterize Borrelia burgdorferi genes important for metabolizing vitamin B2. To accomplish this, Schulz and Jewett (right) examine bacterial colonies on solid medium plates.

Students Driving Discovery

Biomedical sciences doctoral student Anna Schulz ’25MS played a key role in pinpointing specific ways the bacteria use riboflavin to generate energy. She served as first author on a recent publication examining these processes, and says she’s looking forward to growing as a researcher in this next phase.

“As a first author, I took more ownership over the experiments and the writing process,� Schulz says. “[Jewett] was really great about letting me lead the project as a student. Borrelia is so unique, and there’s still so much we don’t know, and that’s what keeps me engaged with this research.�

“… I couldn’t treat it until years after I got infected. So, I truly care about finding new treatments for Lyme disease.” — Grace Easterling, 91³Ô¹ÏÍø biomedical sciences student

Third-year biomedical sciences undergraduate Grace Easterling says she was drawn to Jewett’s lab because she previously developed Lyme disease and suffered tremendous joint pain. She was determined to find a way to protect others.

“It was something that, because we live in Florida, wasn’t caught early because it’s not as common,� Easterling says. “I struggled for a long time to get diagnosed, and I couldn’t treat it until years after I got infected. So, I truly care about finding new treatments for Lyme disease and understanding the bacteria.�

 


Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under award number R01AI099094. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

]]>
Mollie-Jewett Lyme disease research Mollie-Jewett_Anna-Schulz Biomedical sciences doctoral student Anna Schulz ’25MS uses genetic approaches to characterize Borrelia burgdorferi genes important for metabolizing vitamin B2. To accomplish this, Schulz and Jewett examine bacterial colonies on solid medium plates.
120 Students Join 91³Ô¹ÏÍø to Become Physician Knights /news/120-students-join-ucf-to-become-physician-knights/ Tue, 04 Aug 2026 13:16:11 +0000 /news/?p=154542 Chosen from 5,422 applicants, the 120 new M.D. candidates received their undergraduate degrees from Yale, Vanderbilt, Notre Dame, Duke, Case Western and Emory in addition to 91³Ô¹ÏÍø.

]]>
Pepi Dostal was inspired to enter medicine by his grandmother, a physician who cared for her village in the Czech Republic. Often paid with eggs or meat from her patients’ farms, she remains the village matriarch even after retirement.

“I saw what she means to her community,â€� says Dostal, who comes to 91³Ô¹ÏÍø from the University of Washington. “And I wanted to do the same thing for my community.â€�

Dostal was one of 120 new 91³Ô¹ÏÍø College of Medicine students who received their white coats Monday in a traditional celebration that welcomes them as partners in healthcare.

Chosen from 5,422 applicants, the 120 new M.D. candidates received their undergraduate degrees from Yale, Vanderbilt, Notre Dame, Duke, Case Western and Emory in addition to 91³Ô¹ÏÍø. They include scientists, artists, musicians, athletes, global volunteers and EMTs.

A group of students wearing white coats and posing for a photo
91³Ô¹ÏÍø’s M.D. Class of 2030 includes scientists, community volunteers, first responders, athletes and artists.

Monday was the 18th White Coat Ceremony in the history of the medical school, which celebrates its 20th anniversary this year. In his welcome, 91³Ô¹ÏÍø President Alexander N. Cartwright described “what began as a bold vision on undeveloped land in Lake Nona has grown into a thriving Academic Health Sciences Campus and a community focused on improving lives.â€�

And he credited that growth to Deborah German, vice president for health affairs and founding dean, who has announced her transition from both roles. Monday was her last White Coat Ceremony.

“Dr. German helped transform an ambitious vision into the college you join today,â€� he told students, parents, faculty and staff. “Because of her leadership, hundreds of physicians have begun their careers here, thousands of patients have been served, and new partnerships, discoveries, and opportunities have taken shape across Lake Nona and our state. Dr. German, your remarkable legacy will always hold a special place at 91³Ô¹ÏÍø.â€�

The Good Doctor

For every White Coat Ceremony, German has conducted the first class of medical school called “The Good Doctor – A 91³Ô¹ÏÍø Tradition.â€�

Dean Deborah German conducts the first class of medical school at 91³Ô¹ÏÍø — The Good Doctor, a 91³Ô¹ÏÍø Tradition.
Dean Deborah German conducts the first class of medical school at 91³Ô¹ÏÍø — The Good Doctor, a 91³Ô¹ÏÍø Tradition.

She asks first-year students to imagine the person they love most in the world is seriously ill with an undiagnosed condition. What are the traits they want to see in the doctor caring for their beloved? As students name attributes, German writes each word on a blackboard that is displayed in the College of Medicine atrium for the entire year.

The class of 2030 suggested 38 traits, including humble, trustworthy, dedicated, knowledgeable, ethical, determined, compassionate, resilient and innovative.

“This is your contract with your faculty, friends, family, community and each other,� German said, pointing to the board. “Always remember, The Good Doctor lives in each of you. With the guidance of the faculty and your own hard work, you will become The Good Doctor.�

Nelson Jones with his family, including both parents who are nurses and inspired him to go into medicine.
Nelson Jones with his family, including both parents who are nurses and inspired him to go into medicine.

Inspired to Care for Others

As a 91³Ô¹ÏÍø undergraduate, Nelson Jones earned the Order of Pegasus, the university’s top student honor. Today he is a physician-in-training. Both of his parents are nurses, and he described how their care of others – especially in communities of need – inspired him. So did the opportunities 91³Ô¹ÏÍø provides.

“I’m feeling extremely grateful and excited,� he said after receiving his white coat. “This university has built me into the person I am and will continue to build me into the physician I strive to become.�

Vivian Silva-Dallenbach graduated from the University of South Florida with degrees in biomedical sciences and astronomy. She chose 91³Ô¹ÏÍø for medical school because of the college’s new aerospace medicine program. She’s researched how space flight affects the human body.

“Once I saw that 91³Ô¹ÏÍø has an aerospace medicine program, I knew it was a match,â€� she says. “I’m particularly interested in women’s health and how we can provide specialized care for female astronauts.â€�

Dev Patel, another 91³Ô¹ÏÍø alum, says his dreams are inspired by the College of Medicine’s founding dean. “I would like to take a page out of German’s book. She started with almost nothing to work with and she built something amazing here. So as we have such a long road in front of us, I’m hoping to follow in her footsteps and even have a fraction of the impact she did.â€�

]]>
91³Ô¹ÏÍø_-Class-of-2030-White-Coat 91³Ô¹ÏÍø's M.D. Class of 2030 incudes scientists, community volunteers, first responders, athletes and artists. 91³Ô¹ÏÍø_Class of 2030 White Coat_Deb German Dean Deborah German conducts the first class of medical school at 91³Ô¹ÏÍø — The Good Doctor, a 91³Ô¹ÏÍø Tradition. 91³Ô¹ÏÍø_White Coat_Class of 2030_Nelson Jones Nelson Jones with his family, including both parents who are nurses and inspired him to go into medicine.
91³Ô¹ÏÍø Students, VA Doctor Develop AI Tool to Help Doctors Identify Chronic Pelvic Pain /news/ucf-students-va-doctor-develop-ai-tool-to-help-doctors-identify-chronic-pelvic-pain/ Tue, 28 Jul 2026 15:30:57 +0000 /news/?p=154477 Through a yearlong internship, two 91³Ô¹ÏÍø undergraduates created an AI-assisted application that helps guide healthcare providers and patients towards accurate diagnosis of the source of chronic pelvic pain.

]]>
For millions of women living with chronic pelvic pain (CPP), finding answers can take far too long.

Studies have shown the condition affects nearly one in four women worldwide and is linked to dozens of potential disorders involving multiple organ systems. Yet many healthcare providers receive only limited training in diagnosing the source of pain, often leaving patients facing years of uncertainty, repeated testing and ineffective treatments before receiving the right diagnosis.

A yearlong collaboration between a 91³Ô¹ÏÍø physician-scientist and two biomedical sciences undergraduate students aims to create a better environment for doctors and patients to reach an understanding together. Biomedical sciences students Sarah Gabriela Nieto Chavarro and second-year Juliana Dimetry interned with Georgine Lamvu, a 91³Ô¹ÏÍø College of Medicine volunteer professor of obstetrics and gynecology, to transform years of international research into a practical tool to help clinicians evaluate patients more quickly and confidently.

The team is developing an AI-assisted clinical questionnaire application that guides physicians through a patient’s symptoms and identifies which organ systems and conditions should be examined. Rather than replacing a physician’s judgment, the application compiles patient histories quickly to help guide physicians toward making a clearer diagnosis.

From International Research to a Practical Tool

Despite the prevalence of CPP, many healthcare providers lack specialized training in diagnosing the underlying condition because symptoms often overlap with gastrointestinal, urinary, musculoskeletal and reproductive disorders.

“We’re hoping that this can become easy to use and can take a detailed medical history that could take an hour to get through down to just 5 to 10 minutes.� — Georgine Lamvu, volunteer professor and Orlando VA practitioner

“We’re hoping that this can become easy to use and can take a detailed medical history that could take an hour to get through down to just 5 to 10 minutes,� says Lamvu, who practices at the U.S. Department of Veterans Affairs Medical Center in Orlando and directs its gynecological surgery fellowship program and center. “That allows physicians to have a more efficient evaluation and spend more time with the patient.�

The center is a pioneering program designed to address the growing demand for specialized gynecologic care among women veterans. As the number of women veterans using VA healthcare services is expected to increase significantly, this fellowship and center aims to train highly skilled gynecologists to meet their healthcare needs within the VA system and beyond.

As part of that initiative, this project builds upon nearly five years of work led by Lamvu alongside an international coalition of physicians, researchers and patient advocacy groups.

Their research culminated in an international consensus called R U MOVING SOMe, an acronym that categorizes the broad range of symptoms associated with chronic pelvic pain and is the basis of the AI-tool Lamvu and her team developed.

Finding a Definitive Diagnosis

Lamvu says the team translated the clinical research into the logic behind a chatbot-style application that asks fewer than 20 targeted questions. Physicians enter a patient’s symptoms and history into the program, which then suggests the organ systems and conditions most likely responsible for the pain, helping clinicians focus their evaluation.

The team plans to expand the application beyond patient questionnaires by incorporating physical examination findings into the same scoring system. Ultimately, the researchers say they hope it can be used in any practice that serves women, but it may be years away from being realized.

“Physicians just need a way of processing all the information that comes from the patient to narrow it down to a differential diagnosis,â€� Lamvu says. “Right now, it’s all too common to see healthcare workers panic a little when they hear a patient has chronic pelvic pain because it’s considered a complex condition.â€�

Four people posing for a photo
Biomedical sciences students Sarah Gabriela Nieto Chavarro (left) and Juliana Dimetry (right) with Associate Professor of Medicine Kersten Schroeder (second from right), who was instrumental in facilitating the internship with 91³Ô¹ÏÍø College of Medicine Volunteer Professor Georgine Lamvu (second from left) at the Orlando VA.

An Inspiring Internship

The students sifted through years of research and developed the logic for the AI in less than a year. Given the complexity of CPP and the vast amount of data, Lamvu says she is impressed by Dimetry and Nieto Chavarro.

“They learned valuable lessons, like if you see a problem that seems unsolvable to everyone else and that directly and negatively impacts patients, you have the power to do something about it,� she says. “These are experiences not every student gets to have, especially this early on in their life.�

Dimetry says she challenge intrigued her, and that she was drawn to the project for the opportunity to be at the forefront of medicine and emerging technology.

“I think that adapting the field of medicine to AI in ways such as this project is necessary to keep medicine growing and advancing,� she says. “I also saw how impactful this project could be if done successfully, and I wanted to be a part of that and make a difference,�

For Nieto Chavarro, who graduates Summer 2026, the experience showed her how to use technology to help deliver compassionate patient care.

“On a personal level, this experience has taught me to keep going and to never give up,� Nieto Chavarro says. “All of this has ultimately reinforced how essential it is to genuinely listen to patients so they feel safe and understood�

]]>
VA CPP research story with Dr. Lamvu (10) Biomedical sciences students Sarah Gabriela Nieto Chavarro (left), 91³Ô¹ÏÍø College of Medicine Volunteer Professor Georgine Lamvu (second from left) and Juliana Dimetry (right) with Associate Professor of Medicine Kersten Schroeder (second from right), who was instrumental in facilitating the internship. (Photo by Eddy Duryea '13)
91³Ô¹ÏÍø Engineering Students 3D Print Orthopedic Devices to Assist Venezuelan Earthquake Survivors /news/ucf-engineering-students-3d-print-orthopedic-devices-to-assist-venezuelan-earthquake-survivors/ Fri, 17 Jul 2026 13:30:03 +0000 /news/?p=154224 In response to the recent devastating earthquakes in Venezuela, students in the Biomedical Engineering Society are using 3D printing technology to create life-changing orthopedic devices for injured people and animals.

]]>
When two powerful earthquakes struck Venezuela in late June, 91³Ô¹ÏÍø engineering students didn’t wait to be asked how they could help. They turned on a 3D printer.

Students in the , with support from the American Association of Venezuelan Engineers (AAVE), are producing 3D-printed orthopedic devices — including splints, neck braces and animal immobilizers — for people and pets injured in the disaster.

The initiative, called Bracing Venezuela, began after BMES leaders contacted Greco Pinzón, president of AAVE. Pinzon’s dad, who has been volunteering in Caracas, Venezuela’s capital, connected the students with physicians on the ground who identified the types of orthopedic devices most urgently needed.

“… before we knew it, we had a campuswide humanitarian project taking shape.”

“From there, everything snowballed,� says Jannah Barakat, a mechanical engineering major and president of BMES. “We started test printing, organizing volunteers, building a print tracker, reaching out to other student organizations, and before we knew it, we had a campuswide humanitarian project taking shape.�

Since launching the effort, BMES has produced more than 350 devices that have been shipped to clinicians in Venezuela. Smaller items, such as finger and wrist splints, take only a few hours to print and are manufactured flat so they can be easily transported. Once they arrive, clinicians soften the material with hot water and mold each device to fit each patient. Larger devices, such as neck braces and animal leg braces, are printed in multiple sizes and can take up to 10 hours to complete. With volunteers printing from across 91³Ô¹ÏÍø and beyond, multiple devices can be produced simultaneously.

Bracing Venezuela has received support from Mohsen Rakhshan, an assistant professor in and BMES faculty advisor, who opened his lab’s 3D printer for the project. While many volunteers are engineering students, faculty members, 91³Ô¹ÏÍø alumni and 3D-printing hobbyists have also come forward to help.

“One of the coolest things about this project has been watching people from so many different backgrounds come together around one goal,â€� Barakat says. “Whether you’re printing a brace, packing a box, donating supplies or simply helping us spread the word, every contribution helps get these devices into the hands of the people and animals who need them.â€�

“I hope this initiative becomes a model for how engineering students can quickly mobilize to respond to humanitarian needs.”

Those interested in joining the initiative don’t need to own a 3D printer. BMES supplies filament to volunteers who have printers, while others can still make an impact by donating materials, connecting the organization with additional volunteers or helping spread the word.

For Barakat, Bracing Venezuela demonstrates what’s possible when engineering students come together for a greater good.

“I hope this initiative becomes a model for how engineering students can quickly mobilize to respond to humanitarian needs,â€� she says. “Whether it’s supporting communities after natural disasters, helping [less fortunate] populations locally or partnering with organizations in other countries, I’d love to continue using engineering as a way to make healthcare more [widely available] wherever it’s needed.â€�


To join the Bracing Venezuela initiative, email Jannah.barakat@ucf.edu.

]]>
4 91³Ô¹ÏÍø Experts Named 2026 American Academy of Nursing Fellows /news/4-ucf-experts-named-2026-american-academy-of-nursing-fellows/ Tue, 14 Jul 2026 13:37:56 +0000 /news/?p=154198 91³Ô¹ÏÍø has the most inductees among universities in Florida in the new class of fellows of the American Academy of Nursing, which honors the profession’s most accomplished leaders.

]]>
Four faculty members from 91³Ô¹Ï꿉۪s College of Nursing have been selected to receive the profession’s most prestigious recognition of fellows of the American Academy of Nursing (FAAN): Jean Davis ’19PhD, Jacqueline LaManna ’13±Ê³ó¶Ù, Kimberly Navarro and Kaitlyn Rechenberg.

91³Ô¹ÏÍø has the most inductees among universities in Florida in the 2026 American Academy of Nursing Class of Fellows, which includes influential healthcare leaders from across the U.S. and around the world. The induction ceremony will be held on Oct. 10, 2026, during the organization’s annual Health Policy Conference in Washington, D.C.

Fellows are selected through a rigorous nomination and review process, and recognized for substantial contributions to improving health outcomes. With the new cohort, the American Academy of Nursing will have more than 3,600 fellows worldwide dedicated to advancing nursing leadership, innovation and science.

The four new inductees, whose collective works have advanced care across the lifespan from pediatrics to older adults, will join 11 fellows of the American Academy of Nursing on faculty at 91³Ô¹Ï꿉۪s College of Nursing.

Jean Davis ’19PhD

Nursing Associate Professor Jean Davis is advancing public health through her interdisciplinary scholarly work. By working with a collaborative team of public health, psychology, kinesiology and artificial intelligence experts, she has developed and continually improved upon a physical activity habit-forming intervention that tailors cues for movement and optimizes responses to ultimately improve outcomes. This intervention is improving health for veterans and pregnant women, and influencing providers, educators and health systems. Davis is also dedicated to advancing nursing science through active mentorship of 91³Ô¹ÏÍø nursing students and early career scholars.

Jacqueline LaManna ’13±Ê³ó¶Ù

For more than three decades, Family Nurse Practitioner and Adult-Gerontology Primary Care Nurse Practitioner Program Director Jacqueline LaManna ’13±Ê³ó¶Ù has made substantial contributions to advancing diabetes care and self-management education as a provider, educator and researcher. Her scholarly works have been cited more than 250 times and are included in the American Diabetes Association Standards of Care in Diabetes shaping care for pregnant women. In addition, LaManna has helped establish national frameworks for telehealth education for nurse practitioner graduate students that have been accessed more than 4,000 times.

Kimberly Navarro

Lecturer Kimberly Navarro is a certified nurse midwife and board-certified women’s health nurse practitioner who has pioneered community health initiatives to increase healthcare access and improve quality of care for children, adolescents, and pregnant women in the U.S., Guatemala, Haiti, and the Dominican Republic. As program director of the Hispanic serving healthcare professionals graduate certificate at 91³Ô¹ÏÍø, Navarro has increased access to the program, strengthened curriculum, and mentored future healthcare professionals. In addition to her faculty appointment Navarro maintains a clinical practice as founder and president of a technology-driven midwifery-led birth center in Orlando.

Kaitlyn Rechenberg

Associate Professor Kaitlyn Rechenberg is advancing standards of behavioral healthcare for children and adolescents living with complex chronic medical conditions through design and implementation of technology-driven interventions. She pioneered the development and validation of the first precision instrument to differentiate diabetes-specific anxiety symptoms from general anxiety symptoms. She also created a mobile health application to deliver tailored mindfulness training to adolescents living with diabetes. Her scholarly work has been cited in seminal position statements by both the American Diabetes Association and International Society for Pediatric and Adolescent Diabetes and has been cited nearly 800 times across 26 countries.

]]>